Bleeding and thrombosis Preface Bleeding and thrombosis Bleeding and thrombosis Table of contents: Preface Introduction Normal Haemostasis Coagulation Tests Prothrombin Time and INR Activated Partial Thromboplastin Time Fibrinogen Levels Thrombin Time Activated Clotting Time Fibrinogen Degradation Products and D Dimers Thromboelastography Thrombocytopenia in the Intensive Care Unit Introduction to thrombocytopenia Diagnostic approach to thrombocytopenia Approach to the thrombocytopenic patient Management of Thrombocytopenia Heparin Induced Thrombocytopenia (HIT) Introduction Pathophysiology Clinical Syndrome Clinical diagnosis Laboratory diagnosis of HIT Management of HIT and HIT with Thrombosis Antithrombotic medications in the Intensive Care Unit Introduction Antiplatelet agents Vitamin K antagonists (including warfarin) Heparin Danaparoid Fondaparinux Bivalirudin Argatroban Dabigatran Thrombolytics Interruption of anticoagulant and antiplatelet therapy in the ICU Perioperative management of patients receiving vitamin K antag.. Bridging of anticoagulant therapy Perioperative management of antiplatelet therapy Perioperative management of non vitamin K antagonist oral antic. Massive Transfusion Introduction Definitions and diagnosis Therapeutic goals in massive haemorrhage Patient subgroups Complications of Massive Blood Transfusion Organisational aspects of a massive haemorrhage protocol Blood Components Equipment for blood administration Logistics of Blood Supply Pharmacological options in massive haemorrhage Non pharmacological management options Interpretation of coagulation tests during a massive transfusion Controversy and changing practice Management of bleeding and anticoagulation during extracorporeal life support Introduction Overview of extracorporeal life support technology Anticoagulation of ECLS circuits Bleeding during ECLS Thrombosis in the ICU Introduction Venous thromboembolism risk assessment Mechanical Thromboprophylaxis Pulmonary Embolism (PE) Ileo femoral Deep Vein Thrombosis (DVT) Bleeding and thrombosis Preface Bleeding and thrombosis
