Pain, Agitation and Delirium in Intensive Care Preface Pain, Agitation and Delirium in Intensive Care Pain, Agitation and Delirium in Intensive Care Table of contents: Preface Executive Summary Pain What is pain? How do we assess patient’s pain in ICU? How should we manage pain in ICU patients? Agitation Agitation Measuring Agitation and Sedation Titrating Sedative Drugs Other Indications for Sedation Risks of Sedation Sedative Drugs Drug Administration Physical Restraint Delirium in Intensive Care Introduction Why is delirium important? Who is at risk? Preventing and Detecting Delirium Detecting Delirium Managing Delirium Long Term Sequelae of Delirium Dilemmas in defining Delirium Conclusion Drug appendix Context sensitive half time Opioids Paracetamol Non Steroidal Anti Inflammatory Drugs (NSAIDs) Ketamine Benzodiazepines Propofol α2 Agonists Antipsychotics Neuromuscular blockers (NMB) Pain, Agitation and Delirium in Intensive Care Preface Pain, Agitation and Delirium in Intensive Care