Research Pathway Module 3 Preface Introduction Fundamental and Translational Science Practical example. Investigating lung injury Experimental models, trading manipulability for fidelity Examples of experimental models in lung injury research Biological assays Protein assays Proteomics Flow Cytometry Genetics and gene expression Functional Assays Experimental design in fundamental and translational biology Exploratory and descriptive phenotyping of patients In vitro studies to investigate mediators In vivo modelling to investigate biological effects Representing and analysing biological data Conclusions Research Pathway Module 3 Research Fundamentals: Fundamental and translational biology in critical care Table of contents: Preface Introduction Fundamental and Translational Science Practical example. Investigating lung injury Experimental models, trading manipulability for fidelity Examples of experimental models in lung injury research Biological assays Protein assays Proteomics Flow Cytometry Genetics and gene expression Functional Assays Experimental design in fundamental and translational biology Exploratory and descriptive phenotyping of patients In vitro studies to investigate mediators In vivo modelling to investigate biological effects Representing and analysing biological data Conclusions Research Pathway Module 3 Preface Introduction Fundamental and Translational Science Practical example. Investigating lung injury Experimental models, trading manipulability for fidelity Examples of experimental models in lung injury research Biological assays Protein assays Proteomics Flow Cytometry Genetics and gene expression Functional Assays Experimental design in fundamental and translational biology Exploratory and descriptive phenotyping of patients In vitro studies to investigate mediators In vivo modelling to investigate biological effects Representing and analysing biological data Conclusions Research Pathway Module 3