Clinical Pharmacokinetics and Pharmacodynamics Preface Introduction What is pharmacokinetics? Relevant PK parameters for drug dosing Antimicrobial factors Tissue penetration Pharmacokinetics of septic patients What is pharmacodynamics? Minimum inhibitory concentration (MIC) PK/PD Kill characteristics Individual drug classes of antimicrobial agents PK/PD Limitations Concentrations at the site of infection Suppression of resistance Combination antimicrobial regimens Conclusion Clinical Pharmacokinetics and Pharmacodynamics Clinical Pharmacokinetics and Pharmacodynamics Table of contents: Preface Clinical Pharmacokinetics and Pharmacodynamics Preface Introduction What is pharmacokinetics? Relevant PK parameters for drug dosing Antimicrobial factors Tissue penetration Pharmacokinetics of septic patients What is pharmacodynamics? Minimum inhibitory concentration (MIC) PK/PD Kill characteristics Individual drug classes of antimicrobial agents PK/PD Limitations Concentrations at the site of infection Suppression of resistance Combination antimicrobial regimens Conclusion Clinical Pharmacokinetics and Pharmacodynamics
