Clinical Outcome Preface Introduction How to Define and Appropriately Select Clinical Outcome Measures Patient oriented clinical outcomes ICU staff orientated outcomes Society oriented outcomes How to Measure Outcome Survival Beyond survival. Health status and quality of life How to Predict Outcome Severity evaluation and outcome prediction Outcome prediction models Acute Physiology and Chronic Health Evaluation system Simplified Acute Physiology Score system Simplified Acute Physiology Score 3 Mortality Probability Models system Intensive Care National Audit and Research Centre model Scores of evolution Specific scores Use of outcome prediction models Patient selection Collection of predictive variables and hospital outcome Computation of the severity score Transformation of the severity score to a probability of death Evaluating the performance of a severity score Discrimination Calibration Uniformity of fit Poor predictive performance Conclusions How to Measure and Compare Performance of Icus Evaluating the performance of the ICU Limitations of the SMR approach A final comment on performance evaluation Conclusion Clinical Outcome Clinical outcome Table of contents: Preface Clinical Outcome Preface Introduction How to Define and Appropriately Select Clinical Outcome Measures Patient oriented clinical outcomes ICU staff orientated outcomes Society oriented outcomes How to Measure Outcome Survival Beyond survival. Health status and quality of life How to Predict Outcome Severity evaluation and outcome prediction Outcome prediction models Acute Physiology and Chronic Health Evaluation system Simplified Acute Physiology Score system Simplified Acute Physiology Score 3 Mortality Probability Models system Intensive Care National Audit and Research Centre model Scores of evolution Specific scores Use of outcome prediction models Patient selection Collection of predictive variables and hospital outcome Computation of the severity score Transformation of the severity score to a probability of death Evaluating the performance of a severity score Discrimination Calibration Uniformity of fit Poor predictive performance Conclusions How to Measure and Compare Performance of Icus Evaluating the performance of the ICU Limitations of the SMR approach A final comment on performance evaluation Conclusion Clinical Outcome