Haematological emergencies in ICU Part I Preface Thrombotic thrombocytopenic purpura Definition (including TMAs) Pathophysiology Signs and Symptoms Diagnosis Differential diagnosis Management Prognosis Atypical haemolytic uremic syndrome Executive Summary Epidemiology of aHUS Pathophysiology Clinical manifestations Diagnostic workup and differential diagnoses Treatment (in the acute phase) and prognosis Disseminated intravascular coagulopathy Background Understanding DIC Diagnosing DIC Rational Management of DIC in the Light of Trial Data Summary Catastrophic antiphospholipid antibody syndrome Definition Aetiology Pathophysiology Epidemiology Signs and Symptoms Investigations Diagnosis Differential diagnosis Management Prognosis Haematological emergencies in ICU Part I Haematological emergencies in ICU Part I Table of contents: Preface Thrombotic thrombocytopenic purpura Definition (including TMAs) Pathophysiology Signs and Symptoms Diagnosis Differential diagnosis Management Prognosis Atypical haemolytic uremic syndrome Executive Summary Epidemiology of aHUS Pathophysiology Clinical manifestations Diagnostic workup and differential diagnoses Treatment (in the acute phase) and prognosis Disseminated intravascular coagulopathy Background Understanding DIC Diagnosing DIC Rational Management of DIC in the Light of Trial Data Summary Catastrophic antiphospholipid antibody syndrome Definition Aetiology Pathophysiology Epidemiology Signs and Symptoms Investigations Diagnosis Differential diagnosis Management Prognosis Haematological emergencies in ICU Part I Preface Thrombotic thrombocytopenic purpura Definition (including TMAs) Pathophysiology Signs and Symptoms Diagnosis Differential diagnosis Management Prognosis Atypical haemolytic uremic syndrome Executive Summary Epidemiology of aHUS Pathophysiology Clinical manifestations Diagnostic workup and differential diagnoses Treatment (in the acute phase) and prognosis Disseminated intravascular coagulopathy Background Understanding DIC Diagnosing DIC Rational Management of DIC in the Light of Trial Data Summary Catastrophic antiphospholipid antibody syndrome Definition Aetiology Pathophysiology Epidemiology Signs and Symptoms Investigations Diagnosis Differential diagnosis Management Prognosis Haematological emergencies in ICU Part I