Neuromuscular conditions Preface Introduction Identifying and Assessing Weakness Determining the severity of weakness Characterising bulbar involvement Characterising respiratory muscle involvement Determining the cause of weakness Laboratory investigations General Issues In The Management of the Patient with Neuromuscular Disease Predicting acute respiratory failure Airway protection and secretion management Ventilation and weaning Nutrition Thromboprophylaxis Sedation and mobilisation Selected Diseases Precipitating ICU Admission Guillain–Barré syndrome (GBS) Botulism Tetanus Myasthenia Gravis Motor neurone disease Myotonic dystrophy Rhabdomyolysis Drugs and toxins Neuromuscular Complications During and After Critical Illness Intensive Care Unit Acquired Weakness (ICU AW) Prolonged neuromuscular blockade Metabolic and electrolyte disorders Other Critical Care related complications Conclusion Neuromuscular conditions » Preface Neuromuscular conditions Intended Learning Outcomes Neuromuscular conditions Identify causes of acute weakness. Be familiar with the assessments and differential diagnosis in acute weakness. Recognise the common acute and subacute causes of neuromuscular weakness leading to ICU admission. Understand their prognosis and treatment. Recognise the causes of acute weakness appearing after ICU admission. Understand their prognosis and treatment. eModule Information Relevant Competencies from CoBaTrICE Neuromuscular conditions 3.1 Manages the care of the critically ill patient with specific acute medical conditions 3.6 Recognises and manages the patient with neurological impairment 3.10 Recognises and manages the patient following intoxication with drugs or environmental toxins Neuromuscular conditions Preface Introduction Identifying and Assessing Weakness Determining the severity of weakness Characterising bulbar involvement Characterising respiratory muscle involvement Determining the cause of weakness Laboratory investigations General Issues In The Management of the Patient with Neuromuscular Disease Predicting acute respiratory failure Airway protection and secretion management Ventilation and weaning Nutrition Thromboprophylaxis Sedation and mobilisation Selected Diseases Precipitating ICU Admission Guillain–Barré syndrome (GBS) Botulism Tetanus Myasthenia Gravis Motor neurone disease Myotonic dystrophy Rhabdomyolysis Drugs and toxins Neuromuscular Complications During and After Critical Illness Intensive Care Unit Acquired Weakness (ICU AW) Prolonged neuromuscular blockade Metabolic and electrolyte disorders Other Critical Care related complications Conclusion Neuromuscular conditions » Preface