Antimicrobial use in the ICU. Basics of Antimicrobial use Preface Introduction Antimicrobial stewardship Pharmacokinetic and pharmacodynamic issues in critically ill patients Different antibiotic classes Beta lactams Aminoglycosides Fluoroquinolones Co Trimoxazole Vancomycin Polymyxins Diagnosis of Infection and Microbiological sampling, biomarkers Starting therapy When not to start antibiotics in the ICU Antibiotic initiation Source control Adapting therapy De escalation of therapy Duration of therapy Clinical failure Conclusions Antimicrobial use in the ICU. Basics of Antimicrobial use Antimicrobial use in the ICU. Basics of Antimicrobial use Table of contents: Preface Antimicrobial use in the ICU. Basics of Antimicrobial use Preface Introduction Antimicrobial stewardship Pharmacokinetic and pharmacodynamic issues in critically ill patients Different antibiotic classes Beta lactams Aminoglycosides Fluoroquinolones Co Trimoxazole Vancomycin Polymyxins Diagnosis of Infection and Microbiological sampling, biomarkers Starting therapy When not to start antibiotics in the ICU Antibiotic initiation Source control Adapting therapy De escalation of therapy Duration of therapy Clinical failure Conclusions Antimicrobial use in the ICU. Basics of Antimicrobial use